Cell culture needs to be carried out in a sterile environment, and serum, which is a nutrient for cell growth, must also be treated aseptically before it can be used. In order to ensure the sterility of serum, qualified sterile medium bottles must also meet the sterility requirements.

Aseptic medium bottles are generally processed from transparent PET material, with good low temperature resistance and impact resistance, non-toxic and tasteless, high transparency, is an excellent packaging material. In sterilization mode, this kind of bottle will generally choose electron beam irradiation sterilization.

Electron beam irradiation is a technique commonly used to sterilize pharmaceutical packaging products and medical instruments. It works by directing a continuous stream of electrons through the item being sterilized. The transfer of the beam energy breaks the DNA strands in the organism, rendering it inactive and the irradiated item sterile.

The electron beam sterilization method is convenient, mild, effective and can be carried out continuously on the final packaged products. It operates at much lower temperatures than steam sterilization and is suitable for products with hard-to-reach areas (e.g., cartridges with LIDS). It has a much lower degradation risk than gamma rays (due to shorter exposure time); In contrast to ethylene oxide exposure, it eliminates the risk of ethylene oxide absorption and subsequent infiltration into the drug product.

Sterile culture-medium bottles after electron beam sterilization can achieve aseptic state and meet the storage requirements of serum, which is of great significance for the orderly growth of cells.

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