Baffled Erlenmeyer Shake Flask with vent cap

The difference between baffle shake flask and ordinary conical erlenmeyer flask
In the era of rapid development of various technologies, cell culture consumables are also constantly updated and iterated, and the baffle shaker is a relatively novel cell culture consumable. What are the differences between the two standard flasks?
First of all, in terms of shape, both of them adopt a triangular design, and the bottle caps are also divided into two types: sealed caps and breathable caps, and the specifications are roughly the same. The main difference between the two is the bottom of the bottle. The bottom of the ordinary shaker is flat, while the bottom of the baffle shaker has grooves. The raised parts of these grooves form a baffle inside the bottle, so name.
The special design of the baffle flask has two functions. One is to reduce the phenomenon of cell clumping. Shaking with a shaker can effectively reduce the viscosity caused by free DNA and cell debris, and reduce the occurrence of cell clumping growth. In addition, the baffle at the bottom can also prevent the vortex phenomenon generated by the medium during shaking, making the medium more uniform, which also has a certain effect on reducing cell clumping. The second is to increase the amount of dissolved oxygen. The baffle at the bottom of the bottle can increase the amount of dissolved oxygen in the medium, effectively promote the full contact between cells and air, and help cells grow better.

In general, the main difference between baffle shake flasks and ordinary shake flasks is the difference in the bottom of the bottle. The new type of bottle increases the amount of dissolved oxygen and is more suitable for cell lines that require a large amount of oxygen.